asal High Flow therapy for Children with Acute Hypoxemic Respiratory Failure

Phase 3

Completed

• Conditions: Acute respiratory failure; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12618000210279
• Lead Sponsor: Paediatric Critical Care Research Group

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-02-09
• Study Completion: 2020-03-27
• Last Update Posted: 24 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1512

Inclusion Criteria

Children aged 1-4 years of age (up to but excluding 5th birthday) with the clinical diagnosis of an Acute Hypoxemic Respiratory Failure disease process such as acute lower respiratory tract infection or asthma, or pnuemonia as examples, and an oxygen requirement in room air (SpO2 <90/92%)
Included are infants with reactive airway disease >12 months and an oxygen requirement in room air (SpO2 <90/92%). This includes infants >12 months with the diagnosis of bronchiolitis
Informed consent from parents or guardians

Exclusion Criteria

Oxygen requirement and therapy in the emergency department existed for longer than 4 hours prior to inclusion (excludes oxygen given in ambulance or other hospital)
Previous use of NHF therapy
Upper airway obstruction
Craniofacial malformations
Critically ill infants requiring immediate higher level of respiratory support i.e. NIV or invasive ventilation, low level of consciousness.
Basal skull fracture
Cyanotic Heart Disease
Home Oxygen therapy
Apnoeas (defined as requiring respiratory support such as NIV or mechanical ventilation)
Trauma
Cystic Fibrosis
Oncology patients
Palliative Care patients
Child protection case

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital length of stay assessed by medical records[Following discharge from hospital.]