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临床试验/NCT01886326
NCT01886326已完成不适用

Peanut Consumption and Human Weight Management

Purdue University1 个研究点 分布在 1 个国家目标入组 196 人开始时间: 2010年2月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
196
试验地点
1
主要终点
Change in Weight

研究概览

简要总结

Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008). However, peanuts are a high fat, energy dense food and concerns about weight gain are widespread. Although research indicates that other characteristics of peanuts offset these properties, and that peanuts may be incorporated into diets without posing a threat to weight gain (Mattes et al., 2008), concern remains among policymakers, healthcare providers, and consumers. Furthermore, worry exists that eating salted peanuts may elevate blood pressure and that eating honey-roasted peanuts make elevate blood sugar. These fears create substantial obstacles to increased peanut consumption.

Recommendations to increase peanut consumption may be made, but if they are not followed, there will be no impact on health. Additional knowledge is needed on: (1) the acceptability of peanuts consumed on a chronic basis, (2) the chronic intake of moderate levels of peanuts and body weight, and 3) the effects of peanuts on blood pressure and blood sugar. The proposed research will examine the acceptability of long-term inclusion of a single form versus varied forms of peanuts in the diet. It is expected that responses will be varied among individuals with different personality characteristics (e.g., prefer sweet versus savory foods, hedonic versus non-hedonic eaters). A better understanding of how different segments of the population choose to include peanuts in their diet and how to optimize long-term consumption should provide insights for better marketing and improved health. Furthermore, it is anticipated that eating salty peanuts will not raise blood pressure and that eating honey-roasted peanuts will not raise blood sugar. Documenting this will add credibility to the evidence that peanuts do not cause weight gain, as well as reinforce recommendations to increase peanut consumption for their health benefits.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Between 18 and 50 years of age
  • Weight stable (< 3 kg weight change within last 3 months)
  • Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
  • Constant habitual diet patterns within last 3 months
  • Willingness to eat all test foods (peanuts daily for 12 weeks)
  • No allergy to foods provided in the study (peanuts)
  • Not a daily peanut or tree nut consumer
  • Not planning to change use of medications known to influence appetite or metabolism
  • Not diabetic or hypertensive
  • No history of gastrointestinal pathology
  • Non-smoker for one year or more

排除标准

  • 未提供

研究组 & 干预措施

Consumption of 42 g of honey peanuts

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

Consumption of 42 g of 3 diff. varieties

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

Consumption of 42 g of salted peanuts

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

Consumption of 42 g of unsalted peanuts

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

Consumption of 42 g of spicy peanuts

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

Consumption of 42 g of var. of types

Experimental

Consumption of 42 grams of peanuts daily

干预措施: Consumption of 42 grams of peanuts daily (Other)

结局指标

主要结局

Change in Weight

时间窗: 2, 4, 6, 8, 10, and 12 weeks

Change in Blood Lipids

时间窗: 4, 8, and 12 weeks

Change in Blood Pressure

时间窗: 2, 4, 6, 8, 10, and 12 weeks

Change in Hedonics of peanut consumption

时间窗: 12 weeks

Participants will rate their liking of the sample each day using a visual analog scale.

Change in Body Composition

时间窗: 2, 4, 6, 8, 10, and 12 weeks

Change in Fasting Blood Glucose

时间窗: 4, 8, and 12 weeks

Change in Cortisol

时间窗: 4, 8, and 12 weeks

Change in Insulin

时间窗: 4, 8, and 12 weeks

Change in Pulse

时间窗: 2, 4, 6, 8, 10, and 12 weeks

次要结局

  • Personality Questionnaires(At baseline visit)
  • Flavor attribute liking measures(At baseline)
  • Compliance(12 weeks)
  • Appetitive Ratings(4, 8, and 12 weeks)
  • Consumption Parameters(12 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Mattes

Distinguished Prof. Foods and Nutrition

Purdue University

研究点 (1)

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