Epidural Blood Patch - The Effect of Volume
- Conditions
- Post dural puncture headache (PDPH) after inadvertent dural puncture with an epidural needle.Other -
- Registration Number
- ACTRN12605000319673
- Lead Sponsor
- Professor Michael Paech, Professor of Obstetric Anaesthesia, School of Medicine and Pharmacology, University of Western Australia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Obstetric patients.PDPH after a confirmed or likely unintentional dural puncture with an epidural needle. PDPH is defined as A headache with clear postural characteristics (onset or significant exacerbation when erect and relieved or significantly diminished by lying flat). The diagnosis is supported by distribution in the frontal or occipital region, with associated neck ache.Medically suitable and consented for epidural blood patch (EBP) for treatment of PDPH.
Previous EBP related to the same unintentional dural puncture (including prophylactic EBP).Scheduled EBP to be performed within 24 hours or more than 5 days after the unintentional dural puncture.History of significant low or radicular back pain (requiring treatment) during pregnancy.Women in whom a further dural puncture occurs at the time of epidural needle insertion for the EBP. Diagnosis of headache other than PDPH subsequently confirmed.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete or partial relief of headache[Assessed at 2, 4, 24, 48 & 72 hours and 5 days post epidural blood patch]
- Secondary Outcome Measures
Name Time Method The presence of symptoms resulting from the epidural blood patch (e.g. back pain).[Assessed at 4, 24, 48 & 72 hours and 5 days post epidural blood patch.];Functional assessment[At 24, 48, 72 hours and 5 days post epidural blood patch (whether headache is interfering with activities).];Requirement for analgesic medications up to 5 days post epidural blood patch for relief of headache.[];Time of discharge from hospital after epidural blood patch.[]