LUEbeck Registry of Intensive Care Patients - Characterization of the Patients Intestinal MICROBIOME

University of Luebeck1 site in 1 country200 target enrollmentMarch 18, 2019

ConditionsICU Patients

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: ICU Patients
Sponsor: University of Luebeck
Enrollment: 200
Locations: 1
Primary Endpoint: Modification of the microbiome
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of the current study is to analyze the effects of ICU-care on changes in microbiome and the influence of intestinal microbiome changes on short-term and long-term morbidity and mortality of ICU patients.

Registry

clinicaltrials.gov

Start Date

March 18, 2019

End Date

March 18, 2024

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Luebeck

Responsible Party

Principal Investigator

Dr. med. Tobias Graf

Principal Investigator

University of Luebeck

Eligibility Criteria

Inclusion Criteria

•Age ≥18 years
•All patients receiving intensive medical care
•A written informed consent from the patient or two independent doctors or legal guardians.

Exclusion Criteria

•Age \<18 years

Outcomes

Primary Outcomes

Modification of the microbiome

Time Frame: Day 0

The modification of the microbiome using ribosomal 16 S DNA sequencing and clustering for Operational Taxonomic Units (OTU) and calculated Shannon Index