The effect of eight-week sprint exercise snacks a long with caloric restriction on serum bile acids in overweight me
Not Applicable
Recruiting
- Conditions
- Overweight.OverweightE66.3
- Registration Number
- IRCT20231015059733N1
- Lead Sponsor
- The University of Shahid Behshti
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
healthy men.
Body mass index 25-30 kg/m2.
Not participating in regular exercise training during the past 6 months before the implementation of the research project.
Not taking antibiotics in the last 6 months
Exclusion Criteria
History of taking illegal drugs and substances
History of specific diseases such as alcoholic or non-alcoholic fatty liver, gallstones, diabetes, cardiovascular failure, metabolic syndrome, gastrointestinal syndrome
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bile acids, the final product of cholesterol catabolism, are made by liver cells and stored in the gallbladder. In this research, selected species are included, primary bile acid i.e. chenodeoxycholic acid(CDCA), secondary bile acid i.e. lithocholic acid(LCA), bile acid conjugated with glycine i.e. glycocondeoxycholic acid(GCDCA), bile acid conjugated with taurine i.e. taurosodeoxycholic acid(TUDCA), total bile acids(TBA). Timepoint: before and after 8 weeks of intervention and control. Method of measurement: Liquid chromatography-mass spectrometry (LC-MS/MS) and Enzymatic assays.
- Secondary Outcome Measures
Name Time Method