MedPath

The FOCUM human disease model for development of osteoarthritis

Recruiting
Conditions
Osteoarthritis
10023213
Registration Number
NL-OMON55307
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
54
Inclusion Criteria

1) Woman, 2) between 50 and 60 years of age, 3) presently using a combined oral
contraceptive, and 4) started oral contraceptive use before her 45th.

Exclusion Criteria

1) Already known with OA (self-reported or registered by general practitioner),
2) known with inflammatory rheumatic conditions including gout, psoriatic
arthritis or rheumatoid arthritis (self-reported or registered by general
practitioner), 3) having contra-indications for MRI (defined as having a heart
pacemaker, implantable cardiac defibrillator (ICD), mechanical heart valve,
blood vessel prosthesis/stent/coil, metal or device in or on the body which is
not removable, a metallic foreign body in the eye, dental prosthesis with a
magnetic click system in the jaw or claustrophobic), 4) terminal or mental
illness, and 5) inability to give informed consent.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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