Falciformopexy for Treatment Perforated Peptic Ulcer.

Not Applicable

Not yet recruiting

• Conditions: Perforated Peptic Ulcer
• Interventions: Procedure: Falciformopexy for Treatment Perforated Peptic Ulcer

• Registration Number: NCT05715450
• Lead Sponsor: Assiut University

Brief Summary

Use the falciform ligament flap for the treatment of perforated peptic ulcer

Detailed Description

Peptic ulcer perforation (PUP) is one in all the foremost common critical surgical emergencies. The omentum flap is usually wont to cover a PUP. However, the omentum can not be utilized in cases of severe peritonitis or previous surgical removal. this is often the primary study conducted in Vietnam that was designed to analyse the outcomes of patients with PUPs who were treated using the ligament.

In the population, the prevalence of ulcer disease supported physician diagnosis ranges from 0.12% to 1.50%, and hospitalization rates range from 0.10% to 0.19%. ulceration perforation (PUP) is one of the foremost common surgical emergencies worldwide, which is necessitate emergent surgical intervention.

the death rate of PUPs is between 1.3% and 20%, and mortality thanks to a perforation of a gastric ulcer is over mortality because of a perforation of a duodenal ulcer (40% vs 10%) . Some studies have shown that having comorbidities, being over 70 years old, undergoing surgical procedure after 36 h, PUP diameter greater than 1 cm2 and postoperative com- plications are associated with mortality. The technique of using the omental patch for repair PUP is commonest now thanks to mobility and vascularity but is also using the falciform ligament in some cases due to highly vascularity.

The technique of using the falciform ligament for the treatment of PUPs was reported in 1978 by Fry . The purpose of the study was to explain the technique and therefore the results of using the falciform ligament for the treat- ment of PUPs during a large volume surgical centre in Assuit university hospital found the falciform patch to be a successful technique in repair PUP and is assumed to be as effective as omental patch but more advantage because of highly vascular.

Study Timeline

• Study First Submitted: 2022-09-29
• Study First Submitted QC: 2023-02-03
• Study First Posted: 2023-02-08
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-09
• Last Update Posted: 2023-03-10
• Study Start: 2023-05-30
• Primary Completion: 2026-10-23
• Study Completion: 2026-11-23

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Any cases presented with PPU within age from 18 till 70 years.

Exclusion Criteria

• malignancy.
• Previous GIT and liver surgery.
• nonoperative treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Falciformopexy for Treatment Perforated Peptic Ulcer	Falciformopexy for Treatment Perforated Peptic Ulcer	Use falciform ligament flap for repair perforated peptic ulcer

Primary Outcome Measures

Name	Time	Method
Falciformopexy for Treatment Perforated Peptic Ulcer	Baseline	The aim is to decrease incidence of leakage from the perforated peptic ulcer by using the falciform ligament for repair of the perforated peptic ulcer.; Firstly, the investigator will seek to repair the perforation using suture to approximate edges then use falciform ligament as a secound layer to ensure security and prevent postoperative leakage that will lead to peritonitis and death.