Calmodulin Gene Mutations in Patients With Ventricular Arrhythmia of Unknown Origin - A Screening Study

Withdrawn

• Conditions: Ventricular Tachycardia

• Registration Number: NCT01947543
• Lead Sponsor: Region Örebro County

Brief Summary

The aim of this study is to screen a well characterized patient population with ventricular tachycardia of unknown origin and treated with an implantable cardioverter-defibrillator (ICD) for mutations in the calmodulin genes.

Detailed Description

Patients with ventricular tachycardia of unknown origin and treated with an implantable cardioverter-defibrillator (ICD) will be asked to participate in the study. For patients with results showing mutations in the calmodulin genes, family members (parents, siblings and children) will also be asked to participate in the study. For under age patients and relatives who agree to participate, informed consent will also be taken from their custodian.

Study Timeline

• Study First Submitted: 2013-08-27
• Study First Submitted QC: 2013-09-17
• Study First Posted: 2013-09-20
• Study Start: 2017-01
• Status Verified: 2018-04
• Primary Completion: 2018-04
• Study Completion: 2018-04
• Last Update Submitted: 2018-04-10
• Last Update Posted: 2018-04-11

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients with ventricular tachycardia of unknown origin that have been treated with an ICD
• Signed and dated informed consent

Exclusion Criteria

• Inability to provide informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mutations in the calmodulin genes	1 month.

Trial Locations

Locations (1)

Department of Cardiology, Örebro University Hospital; 🇸🇪 Örebro, Sweden