Suboxone (buprenorphine/naloxone) versus methadone opioid rotation in patients with escalated opioid use and chronic pain: a randomized trial.

Recruiting

• Conditions: <p>(Iatrogenic) opioid use disorder, chronic non-malignant pain.</p>; Opioid use disorder, Methadone, Buprenorphine/naloxone, Chronic pain; 10037176

• Registration Number: NL-OMON29667
• Lead Sponsor: Radboudumc

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

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- 18 jaar of ouder. |

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Exclusion Criteria

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- Zwanger, van plan zwanger te worden tijdens de studieperiode of geeft borstvoeding. |

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Effect of suboxone and methadone on self-reported opioid misuse.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Effects of suboxone and methadone on; - pain (pain intensity, central sensitization , functional interference due to pain); - well-being (quality of life, depression, anxiety, stress, opioid craving, physical functioning, cognitive functioning, perceived recovery); - drug/medication use (dose of original and substitution opioids, concomitant drug and medication use); - side effects; - treatment retention.</p><br>