Predicting Failure of High Flow Nasal Cannula in Pneumonia Patients With Hypoxemic Respiratory Failure: The Utility of ROX Index
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 201
- 主要终点
- prediction of need for mechanical ventilation using ROX index
研究概览
简要总结
The purpose of the study was to describe early predictors and to develop a prediction tool that accurately identifies the need for mechanical ventilation in pneumonia patients with acute respiratory failure treated with High Flow nasal cannula.
详细描述
Purpose The purpose of the study is to describe early predictors and to develop a prediction tool that accurately identifies the need for mechanical ventilation (MV) in pneumonia patients with hypoxemic acute respiratory failure (ARF) treated with high-flow nasal cannula (HFNC).
Materials and methods This is a 4-year prospective observational 2-center cohort study including patients with severe pneumonia treated with HFNC. High-flow nasal cannula failure was defined as need for MV. ROX index was defined as the ratio of pulse oximetry/fraction of inspired oxygen to respiratory rate.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of acute respiratory failure secondary to pneumonia receiving HFNC therapy
排除标准
- •younger than 18 years old
- •indication for mechanical ventilation at ICU admission
- •limitation of therapeutic effort
结局指标
主要结局
prediction of need for mechanical ventilation using ROX index
时间窗: through study completion, an average of 1 year
participants will be followed during their stay in the ICU registering the days with HFNC treatment and their need or not for mechanical ventilation.
次要结局
未报告次要终点