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Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery

Not Applicable
Conditions
Anesthesia
Interventions
Procedure: Sciatic nerve anesthesia blockade at bifurcation.
Procedure: Sciatic nerve blockade 2 cm beyond the bifurcation
Device: Insulated Needle, (Stimuplex; Braun, Melsungen, Germany)
Drug: Intravenous analgesics
Procedure: Saphenous nerve block
Registration Number
NCT01734954
Lead Sponsor
CES University
Brief Summary

The purpose of this study is to evaluate the latency period (timing between the injection of the local anesthetic and the onset of complete sensory nerve block) of two approaches for ultrasound-guided popliteal sciatic nerve block: One of the approaches is the injection of the anesthetic just at the site of the bifurcation of the sciatic nerve and the other one is injecting the local anesthetic at least 2 cm beyond the bifurcation of the aforementioned nerve. Our main hypothesis is that the first approach will decrease the latency period, and probably, will increase the success rate of the nerve block as well as patient satisfaction.

Detailed Description

Compare the effectiveness of nerve blockade at the bifurcation site of the sciatic nerve versus distal (tibial and peroneal) using only levobupivacaine 0.5%. The primary outcome is the latency period of the nerve blockade; the secondary outcomes are rate of success of the procedure as well as patient satisfaction.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
66
Inclusion Criteria
  • Patients scheduled for ankle or foot surgery at Hospital Pablo Tobón Uribe and Clínica CES.
  • Physical status classification of the American Society of Anesthesiologists (ASA) 1-3.
  • Age: 18-70 years.
  • Weight: 40-100 kg
  • Taller than 140 cm.
Exclusion Criteria
  • No patient acceptance.
  • Contraindications for nerve block (coagulopathy, local anesthetics allergy, sepsis, infection at the site of puncture).
  • Neuropathy or myopathy affecting the lower limb.
  • Psychiatric or neurological diseases that alter the evaluation of patient.
  • Arrhythmias.
  • Heart failure.
  • Diabetes Mellitus.
  • Pregnancy.
  • Language barriers.
  • Anticoagulation.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Sciatic nerve blockade at bifurcationSciatic nerve anesthesia blockade at bifurcation.Ultrasound-guided block at the bifurcation of the sciatic nerve
Sciatic nerve blockade at bifurcationInsulated Needle, (Stimuplex; Braun, Melsungen, Germany)Ultrasound-guided block at the bifurcation of the sciatic nerve
Sciatic nerve blockade at bifurcationsupplemental oxygenUltrasound-guided block at the bifurcation of the sciatic nerve
Sciatic nerve blockade at bifurcationIntravenous analgesicsUltrasound-guided block at the bifurcation of the sciatic nerve
Sciatic nerve blockade at bifurcationSaphenous nerve blockUltrasound-guided block at the bifurcation of the sciatic nerve
Sciatic block 2 cm beyond bifurcationSciatic nerve blockade 2 cm beyond the bifurcationUltrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Sciatic block 2 cm beyond bifurcationInsulated Needle, (Stimuplex; Braun, Melsungen, Germany)Ultrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Sciatic block 2 cm beyond bifurcationsupplemental oxygenUltrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Sciatic block 2 cm beyond bifurcationIntravenous analgesicsUltrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Sciatic block 2 cm beyond bifurcationSaphenous nerve blockUltrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Sciatic nerve blockade at bifurcationMidazolamUltrasound-guided block at the bifurcation of the sciatic nerve
Sciatic block 2 cm beyond bifurcationMidazolamUltrasound-guided block of the sciatic nerve 2 cm beyond of the bifurcation
Primary Outcome Measures
NameTimeMethod
Latency period of sciatic nerve block.5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes and 30 minutes after nerve block.

Once the nerve blockade is done, a sensory evaluation will be performed in the surgical area every five minutes to determine the onset of the sensory nerve blockade in minutes.

Secondary Outcome Measures
NameTimeMethod
Success of sciatic nerve blockEvery 5 minutes until 30 minutes until the end of the procedure for the nerve block; an additional measure will be performed at the end of of the surgery.

The time to achieve a complete sensory nerve block, reached maximum at 30 minutes, in full distribution of tibial nerve and common fibular nerve for anesthesia.

Patient satisfactionPostoperative 24 hours

Using a categorical score we will measure satisfaction of nerve-block-procedure satisfaction and analgesia quality one day after surgery: patients will choose one of three options: no satisfied, satisfied or very satisfied.

Sensory block5, 10, 15, 20, 25 and 30 minutes after the block is finished

Evaluation in 5, 10, 15, 20, 25 and 30 minutes after the procedure in the distribution of the common peroneal and tibial nerves

0: Complete sensory block

1. Almost complete sensory block: Decreased sensation to pinprick with a 24 gauge hypodermic needle

2. Feeling normal (for each component: tibial and common peroneal) compared with the contralateral leg

Motor block5, 10, 15, 20, 25 and 30 minutes of completion after the block is finished

Evaluation in 5, 10, 15, 20, 25 and 30 minutes after the procedure in the distribution of the common peroneal and tibial nerves 0: Complete motor blockade

1. Motor block almost complete

2. No motor block (for the tibial component for plantarflexion and dorsiflexion with the common peroneal) compared with the contralateral leg

First analgesic5 minutes, 30 minutes, 24 hours postoperative

Time of first analgesic requirement in postoperative

Visual analog scale at rest5 minutes, 30 minutes, 24 hours postoperative

Pain rating ranging from zero to ten VAS 0: no pain VAS 1-3: Mild pain VAS 4-6: Moderate Pain VAS 7-10: Severe pain

Dynamic visual analog scale5 minutes, 30 minutes, 24 hours postoperative

Pain rating ranging from zero to ten with the movement

Intraneural injectionAt the time of injection and execution of the block

Increased diameter nerve or visualized by ultrasound visualization of the needle into the nerve at the time of injection

Vascular punctureDuring the execution of the block

Puncture of one or more blood vessels to visualize the needle within the vessel or to aspirate blood during block

Paresthesia during the procedureAt the time of the execution of the block

Paresthesia during the procedure

Systemic toxicity of local anestheticsDuring the execution of the block and 30 minutes after it

Systemic toxicity of local anesthetics

HematomaDuring and inmmediately after the execution of the block

Hematoma

Muscle weakness24 hours postoperative

Subjective reduction in muscle strength at 24 hours postoperative

Altered sensitivity24 hours postoperative

Subjective decreased sensitivity at 24 hours postoperative

Cramps postoperative24 hours postoperative of the block

Feeling cramps within 24 hours of the block

PuncturesDuring the block

Number of skin punctures during the block

Time for the execution of nerve blockIn minutes: Time from placement of the transducer for the initial scan to final withdrawal of the needle

Time from placement of the transducer for the initial scan to final withdrawal of the needle

Trial Locations

Locations (2)

Hospital Pablo Tobón Uribe

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Medellín, Antioquia, Colombia

Clínica CES

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Medellín, Antioquia, Colombia

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