Oxygen

California Institute of Technology researchers successfully transitioned their iCares smart bandage system from animal models to human clinical testing, enrolling 20 patients with diabetic foot ulcers and venous leg wounds.

City of Hope has opened a phase 1 clinical trial called DINOMITE to test papaverine, an investigational drug that sensitizes tumor cells to radiation therapy by blocking oxygen consumption in cancer cells.

• USF Health has initiated a $28 million clinical trial to evaluate hyperbaric oxygen therapy (HBOT) for traumatic brain injury (TBI) in Florida veterans and service members. • The five-year, double-blind, placebo-controlled study will monitor physiological signs to assess HBOT's effectiveness, with placebo participants offered HBOT treatment post-study. • Championed by Florida House Speaker Paul Renner, the trial aims to provide definitive scientific evidence on HBOT's efficacy for TBI and potential benefits for the broader community. • The study, led by Dr. Harry van Loveren, involves a multidisciplinary team and leverages USF Health's extensive TBI research expertise to maximize research investment return.

A retrospective study indicates that hyperbaric oxygen therapy (HBOT) demonstrates an 86.9% response rate as an adjunctive treatment for late-onset hemorrhagic cystitis (HC) following allogeneic hematopoietic stem cell transplantation (HSCT).

A clinical trial is underway at the University of Miami Miller School of Medicine, among 15 sites, to assess hyperbaric oxygen therapy (HBOT) for ulcerative colitis treatment.