Medication Review in patients with Polypharmacy in primary care: Effects of the Clinical Rules Engine and the Outcome Prioritisation Tool on Patient and Clinical Outcomes: CRE-OPT study

Withdrawn

• Conditions: polyfarmacie; daily use of 5 medications or more; Polypharmacy

• Registration Number: NL-OMON46017
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 360

Inclusion Criteria

Patients aged * 60 years with at least 5 chronic medication prescriptions in at least two different organ systems.

Exclusion Criteria

Patients who cannot act for themselves, patients with insufficient knowledge of Dutch language,
patients with a life-expectancy of less than one year.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome measure is treatment satisfaction measured with the<br /><br>Treatment Satisfaction Questionnaire for Medication (TSQM-II). .</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome measures are:<br /><br>a. Patient related: medication adherence, measured with the Medication<br /><br>Adherence Report Scale (MARS-5), and quality of life measured with EQ-5D .<br /><br>b. Medication related: Drug Burden Index, changes in medication prescriptions,<br /><br>number and type of alerts (all extracted by CRE).<br /><br>c. Process related: time needed in general practice (by GP and nurse<br /><br>practitioner) and by the community pharmacist; number of contacts between GP<br /><br>and medical specialist to discuss medication changes; satisfaction of patients<br /><br>and professionals with CRE-OPT.</p><br>