The Microbial Profile Among Patients Before and After Partial Maxillectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 主要终点
- microbial types
研究概览
简要总结
Patients after maxillecotmy develop gum disease and teeth decay often. these two diseases are caused by bacteria. In addition, these patients may have oral infections such as candida . The therapeutic approach now days to these diseases (dental decay and periodontal disease) can change following the results of the study.
the purpose of the study is to examine whether the connection between the oral cavity and anatomical structures exposed by maxillectomy procedure causes a change in the level of microbes examined. To the best of our knowledge, there are not yet studies examined the clinical and microbiological changes in the oral cavity before and after surgery.
详细描述
This study will include 15 patients who are scheduled to undergo partial maxillectomy as part of a prescribed treatment program prior to their eligibility for the study. The patients will undergo the surgery at the Department of Otolaryngology or Oral and Maxillofacial Surgery and will be given an obturator during surgery by a physician from the Internal and Maxillofacial Rehabilitation Department of the School of Dentistry .
demographic data on the patient's age and gender, general medical history, smoking habits, oral and periodontal and clinical examination (presence of periodontal disease) and microbiological testing will be preformed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •signed Consent form
- •Patients who are supposed to undergo Maxilla removal without closing the defect using a tissue implant and will need to complete the missing area by an obturator.
- •Men and women aged 18 and over
排除标准
- •Allergy to substances from which the obturator is made.
- •Pregnant women
- •Taking antibiotic drugs that affect bacterial flora 4 weeks before taking the saliva sample.
- •Psychiatric problem
研究组 & 干预措施
before and after partial maxillectomy
Microbial profile among patients before and after partial maxillectomy
干预措施: Microbial profile (Diagnostic Test)
结局指标
主要结局
microbial types
时间窗: 6 months
types of microbes on the sliva
次要结局
未报告次要终点