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临床试验/NCT00471796
NCT00471796Unknown不适用

A Comparison of Factors of Symptoms Generation and Evaluation of Role of Biofeedback in Patients With Different Types of Functional Esophageal Disorders (Functional Heartburn and Functional Chest Pain)

Assaf-Harofeh Medical Center0 个研究点开始时间: 2007年5月10日最近更新:
适应症

试验速览

阶段
不适用

研究概览

简要总结

There is supposed that patients with functional esophageal disorders such as functional heartburns and functional chest pain have common underlying mechanisms of symptom generation. These include esophageal dysmotility, non-acidic gastro-esophageal reflux, duodeno-gastro-esophageal reflux, esophageal hypersensitivity, and psychological comorbidity.

The treatment of these patients is the growing challenge in the primary care medicine and in the gastroenterological practice. It was postulated that functional disorders of the esophagus are the main reason for PPI failure in patients with heartburn.

The aim of the study is to evaluate the role of biofeedback in the treatment of patients with functional chest pain and functional heartburns.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Men and women ages 18-
  • Willing to participate and sign an inform consent.
  • Having heartburns, acid regurgitations and/or chest pain at least twice a week for at least 3 months.
  • Ability to stop anti-acid and anti-pain medications for at least two weeks.

排除标准

  • History of upper gastrointestinal surgery.
  • Concomitant diseases that may affect esophageal perception (diabetes mellitus, neuropathy).
  • Concomitant medications that may affect esophageal perception (anti-inflammatory, anti-depressants drugs).
  • Severe conditions such as cardiac failure, renal failure and other that may be contraindication for upper endoscopy.
  • Erosive esophagitis on upper endoscopy or pathological result of ambulatory 24-hour pH monitoring.

研究者

申办方类型
Other Gov

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