Influence of Sleep Regularity on Circadian Rhythms, Learning, Performance, and Mood
Not Applicable
Active, not recruiting
- Conditions
- Physiology
- Interventions
- Other: Sleep/Wake Schedule
- Registration Number
- NCT02839070
- Lead Sponsor
- Brigham and Women's Hospital
- Brief Summary
The study is a combination of outpatient and inpatient monitoring. During the 27-day inpatient portion of the study, the individual's sleep-wake schedule will be varied daily. Volunteers will be randomized to a regular or irregular inpatient schedule.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
- healthy
- BMI between 18.5 and 29.5
Exclusion Criteria
- medications
- recent night-work, shift-work, or travel across >2 time zones
- use of medications
- pregnant or within 6 months post-partum
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Irregular Schedule Sleep/Wake Schedule Participant will be on an irregular sleep/wake schedule Regular Schedule Sleep/Wake Schedule Participant will be on a regular sleep/wake schedule
- Primary Outcome Measures
Name Time Method Mood 27 days Mood (using a linear non-numeric scale) across difference days inpatient portion of the experiment
Circadian phase 27 days Circadian phase, as measured by melatonin, at end vs. beginning of inpatient portion of experiment
Learning 27 days Sleep-dependent learning at 3-4 times during inpatient portion of the experiment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States