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Influence of Sleep Regularity on Circadian Rhythms, Learning, Performance, and Mood

Not Applicable
Active, not recruiting
Conditions
Physiology
Registration Number
NCT02839070
Lead Sponsor
Brigham and Women's Hospital
Brief Summary

The study is a combination of outpatient and inpatient monitoring. During the 27-day inpatient portion of the study, the individual's sleep-wake schedule will be varied daily. Volunteers will be randomized to a regular or irregular inpatient schedule.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
27
Inclusion Criteria
  • healthy
  • BMI between 18.5 and 29.5
Exclusion Criteria
  • medications
  • recent night-work, shift-work, or travel across >2 time zones
  • use of medications
  • pregnant or within 6 months post-partum

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Mood27 days

Mood (using a linear non-numeric scale) across difference days inpatient portion of the experiment

Learning27 days

Sleep-dependent learning at 3-4 times during inpatient portion of the experiment

Circadian phase27 days

Circadian phase, as measured by melatonin, at end vs. beginning of inpatient portion of experiment

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Brigham and Women's Hospital

🇺🇸

Boston, Massachusetts, United States

Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States

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