ACTRN12618001320246
Completed
N/A
OPtimisation of Perioperative Cardiovascular Management to Improve Surgical outcomE II trial (Optimise II) - biomarker sub-study for Australian sites
St Vincent's Hospital Melbourne0 sites103 target enrollmentAugust 6, 2018
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Postoperative infection
- Sponsor
- St Vincent's Hospital Melbourne
- Enrollment
- 103
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients who have consented and recruited to the OptimiseII trial which includes
- •patients aged 65 years and over undergoing major elective surgery involving the gastrointestinal tract that is expected to take longer than 90 minutes.
Exclusion Criteria
- •Inability or refusal to provide patient consent
- •clinician refusal (including intention to monitor cardiac output from the start of surgery regardless of study group allocation)
- •American Society of Anesthesiologists (ASA) score of I
- •patients expected to die within 30 days
- •acute myocardial ischaemia within 30 days prior to randomisation
- •acute pulmonary oedema within 30 days prior to randomisation
- •contra\-indication to low\-dose inotropic medication
- •pregnancy at time of enrolment
- •current participation in another clinical trial of a treatment with a similar biological mechanism or primary outcome measure
Outcomes
Primary Outcomes
Not specified
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