Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual Environments
- Conditions
- Cerebrovascular AccidentHemiplegiaHemiparesis
- Registration Number
- NCT01072461
- Lead Sponsor
- New Jersey Institute of Technology
- Brief Summary
The complexity of sensorimotor control required for hand function as well as the wide range of recovery of manipulative abilities makes rehabilitation of the hand most challenging. The investigators past work has shown that training in a virtual environment (VE) using repetitive, adaptive algorithms has the potential to be an effective rehabilitation medium to facilitate motor recovery of hand function. These findings are in accordance with current neuroscience literature in animals and motor control literature in humans. The investigators are now in a position to refine and optimize elements of the training paradigms to enhance neuroplasticity. The investigators first aim tests if and how competition among body parts for neural representations stifles functional gains from different types of training regimens. The second aim tests the functional benefits of unilateral versus bilateral training regimens.The third aim tests whether functional improvements gained from training in a virtual environment transfer to other (untrained) skills in the real world.
- Detailed Description
The complexity of sensorimotor control required for hand function as well as the wide range of recovery of manipulative abilities makes rehabilitation of the hand most challenging. The investigators past work has shown that training in a virtual environment (VE) using repetitive, adaptive algorithms has the potential to be an effective rehabilitation medium to facilitate motor recovery of hand function. These findings are in accordance with current neuroscience literature in animals and motor control literature in humans. The investigators are now in a position to refine and optimize elements of the training paradigms to enhance neuroplasticity. The investigators first aim tests if and how competition among body parts for neural representations stifles functional gains from different types of training regimens. The second aim tests the functional benefits of unilateral versus bilateral training regimens.The third aim tests whether functional improvements gained from training in a virtual environment transfer to other (untrained) skills in the real world.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
- Six months post cerebrovascular accident
- Residual upper extremity impairment that affects participation
- At least ten degrees of active finger extension
- Tolerate passive shoulder flexion to chest level
- Severe neglect
- Severe aphasia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change in Jebsen Test of Hand Function Two Weeks Prior to Training, Immediately Prior to Training, Immediately After Training, 3 Months After Training
- Secondary Outcome Measures
Name Time Method Change in Box and Blocks Test Two Weeks Prior to Training, Immediately Prior to Training, Immediately After Training, 3 Months After Training Change in Robotically Collected Kinematics 1 day before training and 1 day after training Change in Wolf Motor Function Test Two Weeks Prior to Training, Immediately Prior to Training, Immediately After Training, 3 Months After Training Change in Reach to Grasp Test 1 day before training and 1 day after training Change in 9 Hole Peg Test Two Weeks Prior to Training, Immediately Prior to Training, Immediately After Training, 3 Months After Training
Trial Locations
- Locations (1)
New Jersey Institute of Technology
🇺🇸Newark, New Jersey, United States
New Jersey Institute of Technology🇺🇸Newark, New Jersey, United States