The effect of Repetitive transcranial magnetic stimulation (r-TMS) in the Dorsolateral Prefrontal Cortex (DLPFC) on the symptoms of patients with obsessive-compulsive disorder
- Conditions
- Obsessive-compulsive disorder.Obsessive-compulsive disorder
- Registration Number
- IRCT20230508058128N1
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Definitive diagnosis of OCD based on the DSM V diagnostic criteria by two psychiatrists (clinical interview)
obtaining a score equal to or greater than 16 from the Y-BOCS questionnaire,
not taking related drugs in the last four weeks and starting drug treatment with sertraline 150 mg (simultaneously to along with r-TMS for the intervention group),
not receiving ECT in the past 6 months and the willingness of the subjects to participate in the research
Existence of accompanying psychiatric disorder, especially depression (based on Beck Depression Scale) score of Beck Questionnaire above 10, suffering from seizures
use of drugs and substances, presence of metal implants, pacemaker, trauma or head injury and neurosurgery procedures
incompleteness of patients data more than 10%
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Yale-Brown Obsession Scale. Timepoint: Before the start of the study, after each RTMS session, 3 months after the last session. Method of measurement: Using a standard questionnaire.
- Secondary Outcome Measures
Name Time Method Quality of Life Brief Version (WHOQOL-BREF). Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Symptoms of obsession. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.;Beck depression questionnaire 2. Timepoint: Before the intervention, after each session, 3 months after the last session. Method of measurement: Based on a standard questionnaire.