MedPath

Home-Based Exercise Gaming for Physically Inactive Individuals

Not Applicable
Completed
Conditions
Physical Inactivity
Interventions
Behavioral: Home-based exergaming
Registration Number
NCT04633590
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Brief Summary

Current guidelines recommend that adults undertake at least 150 minutes of moderate intensity physical activity or 75 minutes of vigorous physical activity per week. However, many adults fail to be physically active according to this definition of the World Health Organisation (WHO). This represents a large economic burden to healthcare systems and public health. A number of behavioural and environmental factors associated with modern lifestyles are largely responsible for the high levels of physical inactivity including; motorised transport and sedentary jobs, lack of time, limited access to adequate exercise facilities, lack of motivation, financial constraints and environmental factors including bad weather. In an attempt to overcome many of the common barriers to exercise, members of our research group developed a virtually-monitored exercise intervention that used simple on-the-spot bodyweight exercises to be performed in the participant's home without supervision or equipment. This home-based intervention was designed to be a practical and effective training strategy capable of producing metabolic and functional adaptions while removing many of the common barriers to exercise. Despite promising results, more engaging exercise strategies are needed to motivate sedentary individuals to increase their physical activity.

Inspired by current trends in the fitness market, Sphery Ltd. developed an immersive and motivating fitness exercise game (exergame), the "ExerCube". The ExerCube allows a full-body workout that concurrently challenges physical and cognitive functions and adapts to the fitness and skill level of the individual. The development of a home-based version of the ExerCube has the potential to make this system available to more individuals, reduce major barriers to exercise, and ultimately provide a strategy to improve cardio-metabolic health in the population. Innovative home-based exergames are particularly in demand given the increase in the number of people wanting to exercise at home due to the COVID-19 pandemic.

Detailed Description

Current guidelines recommend that adults undertake at least 150 minutes of moderate intensity physical activity or 75 minutes of vigorous physical activity per week. Regular physical activity improves many cardiovascular and metabolic health makers including beneficial effects on body weight, insulin sensitivity, glycaemic control, lipid profile, endothelial function and aerobic capacity. Despite overwhelming evidence that an inactive lifestyle leads to chronic disease and premature death, many adults fail to meet physical activity guidelines. Physical inactivity, defined as physical activity levels less than those required for optimal health and prevention of premature death, is a public health crisis. More than 1.4 billion adults worldwide classed as physically inactive, representing a large economic burden to healthcare systems. Clearly, new strategies are urgently needed to increase physical activity participation in the increasingly inactive population.

A number of behavioural and environmental factors associated with modern lifestyle including urbanisation, mechanisation and increased motorised transport are largely responsible for the high prevalence of physical inactivity, in addition to a number of common exercise barriers. Lack of time is cited as the main barrier to exercise as many individuals feel that increasing work hours and family commitments mean they cannot achieve the physical activity guidelines. Other common barriers within the general population include limited access to exercise facilities and appropriate equipment, difficulty with transportation, inadequate financial resources, bad weather and lack of motivation to engage in regular exercise. In an attempt to overcome many of the common barriers to exercise, members of our research group developed a virtually-monitored exercise intervention that used simple on-the-spot bodyweight exercises that could be performed in the participant's home without supervision or equipment. This home-based intervention was designed to be a practical and effective training strategy capable of producing metabolic and functional adaptions while removing many of the common barriers to exercise uptake and adherence such as "intimidating" gym environments, difficulty with access to facilities, travel time and financial constraints. Although these pilot studies successfully reduced common exercise barriers, more engaging exercise strategies are needed to increase levels of physical activity in the physically inactive population.

Inspired by current trends in the fitness market, the Swiss company Sphery Ltd. developed an immersive and motivating fitness exercise game (exergame), the "ExerCube". The ExerCube provides a full-body workout that concurrently challenges physical and cognitive functions as well as adapting to the individuals' fitness and skill level. Previous research has shown that the ExerCube is an effective training method that is more enjoyable than conventional exercise training. Development of a home-based version of the ExerCube has the potential to make this system available to more individuals, and to reduce major barriers to exercise, providing an attractive strategy to improve cardio-metabolic health of the population. Innovative home-based exergames are in demand given the increase in the number of people wanting to exercise at home due to the COVID-19 pandemic.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
27
Inclusion Criteria
  • Male or female
  • Aged 18-55
  • Physically inactive, defined as not meeting the exercise guidelines of 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity per week
  • BMI 18.5 kg/m2 - 30 kg/m2
  • No known cardiovascular disorders
  • Able to provide written informed consent and understand instructions
Exclusion Criteria
  • Overt diabetes mellitus (type 1, type 2, other forms of diabetes)
  • Pregnant, planning on becoming pregnant during the study, or breast feeding
  • Physical or psychological disease likely to interfere with the normal conduct of the study as judged by the investigator

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
home-based exergamingHome-based exergamingThe home-based exergame intervention will take place in an unsupervised place of the participant's choosing. Participants will be provided with all of the equipment (including a television if required) and receive instructions on how to use the system. Participants will be provided with a stepped training plan with exergame session durations of 19 minutes (4x 3-minutes 45-seconds of exercise interspersed with 1 minute of rest) in weeks 1 and 2; 24-minutes (4x 5-minutes of exercise interspersed with 1 minute of rest) in week 3 and 4; and 30-minutes (5x 5-minutes of exercise interspersed with 1 minute of rest) in week 5 and 6. Sessions will be set at a vigorous intensity (≥80% heart rate maximum) and participants will be provided with individualised heart rate zones to achieve in line with heart rate maximum determined during a maximal exercise test in Visit 2. Participants will be asked to train 3 times per week.
Primary Outcome Measures
NameTimeMethod
VO2maxPre to post 6 weeks of home-based exergame training

Change in maximal aerobic capacity (VO2max)

Secondary Outcome Measures
NameTimeMethod
Drop-out rate6 weeks training

Number of participants that drop out from the study

Qualitative interviewsFollowing 6 weeks of training

Overall experience determined through qualitative interviews

Whole body adipose tissuePre to post 6 weeks of home-based exergame training

Change in whole body adipose tissue volume using InBody body composition analyser

Fat free massPre to post 6 weeks of home-based exergame training

Change in fat free mass using InBody body composition analyser

C-reactive proteinPre to post 6 weeks of home-based exergame training

Change in C-reactive protein

Adherence6 weeks of training

Training adherence indicated by the number of training sessions in which the desired exercise intensity was achieved over the 6 week period

Mean daily glucose concentration and area under the glucose curvePre to post 6 weeks of home-based exergame training

Change in mean daily glucose concentration and area under the glucose curve

Mean Daily stepsPre to post 6 weeks of home-based exergame training

Change in daily steps monitored by an accelerometer in percent

Low Density LipoproteinPre to post 6 weeks of home-based exergame training

Change in low density lipoprotein

High Density LipoproteinPre to post 6 weeks of home-based exergame training

Change in high density lipoprotein

Physical Activity Enjoyment Scale (PACES) scorePre to post 6 weeks of home-based exergame training

Change in Physical Activity Enjoyment Scale (PACES) score (an 18-item scale designed to measure physical activity enjoyment)

Immersive Experience Questionnaire (IEQ)Following 6 weeks of training

Immersive experience during home-based exergame sessions

Executive FunctioningPre to post 6 weeks of home-based exergame training

Change in reaction time determined using Test for Attentional Performance

Visceral adipose tissuePre to post 6 weeks of home-based exergame training

Change in visceral adipose tissue mass using InBody body composition analyser

Total cholesterolPre to post 6 weeks of home-based exergame training

Change in total cholesterol

TriglyceridesPre to post 6 weeks of home-based exergame training

Change in triglycerides

HbA1cPre to post 6 weeks of home-based exergame training

Change in HbA1c

Fasting glucose concentrationPre to post 6 weeks of home-based exergame training

Change in fasting glucose concentration

Fasting insulin concentrationPre to post 6 weeks of home-based exergame training

Change in fasting insulin concentration

WmaxPre to post 6 weeks of home-based exergame training

Change in maximal power output (Wmax)

Situation Motivation Scale (SIMS)Pre to post 6 weeks of home-based exergame training

Change in Situation Motivation Scale (SIMS) score

Dynamic balancePre to post 6 weeks of home-based exergame training

Change in dynamic balance determined using Y-Balance Test

Blood pressurePre to post 6 weeks of home-based exergame training

Change in blood pressure (systolic, diastolic and mean)

Coefficient of variationPre to post 6 weeks of home-based exergame training

Change in coefficient of variation in continuous glucose monitor

Trial Locations

Locations (1)

Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland

🇨🇭

Bern, Switzerland

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