Clinical and genetic study of defective gonadal development or function due to inadequate secretion of pituitary gonadotropins
Not Applicable
- Conditions
- Health Condition 1: null- Idiopathic Hypogonadotropic Hypogonadism
- Registration Number
- CTRI/2013/02/003381
- Lead Sponsor
- Diamond Jubilee Society Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Subjects presenting with poor secondary sexual characteristics with
a) Low Testosterone /Low Estradiol
b) Low or inappropriately normal FSH,
c) Low or inappropriately normal LH
Exclusion Criteria
Patient with HH due to
1. Tumors
2. Infiltrative/Inflammatory disorders
3. Trauma
4. Radiation
5. Post surgery
6. Functional gonadotropin deficiency
7. Combined pituitary hormone deficiency
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Help in understanding the genetic basis of the disorder in Indian patients with IHH. Genetic counseling of the first degree relativesTimepoint: 5 years
- Secondary Outcome Measures
Name Time Method The information so obtained will be used to construct a practical and cost-effective flow-chart for genetic testing and counseling in Indian patients.Timepoint: 5 years