A Comparative Study among Intravenous Lignocaine, 2% Lignocaine Nebulisation and 4% Lignocaine Nebulisation in blunting of Laryngeal Response during Intubation, randomised clinical trial

Not yet recruiting

• Conditions: Other general symptoms and signs,

• Registration Number: CTRI/2021/09/036202
• Lead Sponsor: Pondicherry Institute of Medical Sciences

Brief Summary

Effect of Lignocaine airway nebulisation vs intravenous lignocaine on intubation response in General Anaesthesia patients, a comparative randomised clinical trial.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-01-09
• Study Start: 2021-09-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• 1)Patients aged between 18 and 60 yrs.
• 2)American Society of Anaesthesiologists ASA 1 and ASA 2 patients coming for GA.
• 3)Patients coming for elective procedures.

Exclusion Criteria

• 1. Surgery involving the oral, nasopharyngeal, laryngotracheal airway or thyroid.
• 2. Patients history of respiratory disease (COPD, asthma).
• 3. History of recent respiratory tract infection.
• 4. Patients with anticipated difficult intubation and Those requiring > 3 attempts at laryngoscopy and intubation.
• 5. History of any known allergy to Lignocaine.
• 6. Patients coming for emergency procedures.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary objective: To compare hemodynamic responses to Intubation in topical	Baseline, 1min, 2min, 3min, 4min, 5min, 10min.
2% lignocaine and 4% lignocaine patients and compare it with intravenous lignocaine	Baseline, 1min, 2min, 3min, 4min, 5min, 10min.
in patients undergoing General anaesthesia.	Baseline, 1min, 2min, 3min, 4min, 5min, 10min.

Secondary Outcome Measures

Name	Time	Method
To study any adverse drug reactions	1min, 2min, 3min, 4min, 5min, 10min

Trial Locations

Locations (1)

Pondicherry Institute of Medical Sciences; 🇮🇳 Pondicherry, PONDICHERRY, India

Pondicherry Institute of Medical Sciences

🇮🇳Pondicherry, PONDICHERRY, India

Ravichandra Kumar Davuluri

Principal investigator

9786287000

vinay.ravichandra@gmail.com