NCT02995096已完成不适用
The Effect of Tumor Characteristics, Pre-transplant Treatments and Immunosuppression on Survival After Liver Transplantation for Hepatocellular Carcinoma - a European Registry Study
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23,124
- 主要终点
- Overall survival
研究概览
简要总结
Recurrence after liver transplantation for hepatocellular carcinoma (HCC) represents an important cause of mortality for this surgical population. In addition to tumor characteristics, It has been suggested that pre-treatment and sirolimus-based immunosuppression may affect recurrence and survival. With data from the European Liver Transplant Registry (ELTR) database, the aim of this study is to investigate the impact of tumor characteristics, pre-transplant treatment and immunosuppression regimens on survival after liver transplantation for HCC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hepatocellular carcinoma within transplantation criteria
排除标准
- •Disseminated disease
结局指标
主要结局
Overall survival
时间窗: up to 10 year survival
次要结局
- Hepatocellular carcinoma specific survival(5 year and 10 year survival)
研究者
Hans-Christian Pommergaard, MD, PhD
Resident
Rigshospitalet, Denmark
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