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临床试验/NCT02995096
NCT02995096已完成不适用

The Effect of Tumor Characteristics, Pre-transplant Treatments and Immunosuppression on Survival After Liver Transplantation for Hepatocellular Carcinoma - a European Registry Study

Rigshospitalet, Denmark0 个研究点目标入组 23,124 人开始时间: 2016年1月最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
23,124
主要终点
Overall survival

研究概览

简要总结

Recurrence after liver transplantation for hepatocellular carcinoma (HCC) represents an important cause of mortality for this surgical population. In addition to tumor characteristics, It has been suggested that pre-treatment and sirolimus-based immunosuppression may affect recurrence and survival. With data from the European Liver Transplant Registry (ELTR) database, the aim of this study is to investigate the impact of tumor characteristics, pre-transplant treatment and immunosuppression regimens on survival after liver transplantation for HCC.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Hepatocellular carcinoma within transplantation criteria

排除标准

  • Disseminated disease

结局指标

主要结局

Overall survival

时间窗: up to 10 year survival

次要结局

  • Hepatocellular carcinoma specific survival(5 year and 10 year survival)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hans-Christian Pommergaard, MD, PhD

Resident

Rigshospitalet, Denmark

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