Effect of the Use the Acapella Device in Regional Lung Deposition of Radio-aerosol
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 10
- Primary Endpoint
- Radioaerosol regional pulmonary deposition
Study Overview
Brief Summary
Background:
Devices used to facilitate mucus mobilization have been target of several controversies and mainly a few scientific studies that endorse the use of those equipments. According to the principle of acapella® device, it should be used concomitant with nebulization aiming to optimize its performance in bronchial hygiene.
Aims: To assess the effect of acapella® device application in the radioaerosol regional pulmonary deposition through pulmonary scintigraphy in normal subjects.
Materials and method: 10 health individuals, males and mean age of 24,4 ± 2,2 years participated in this study during the three phases of this research: 1st phase were done with nebulization through acapella® device, attached in the final branch according to manufacturer recommendation; in 2nd phase a ¨T¨tube connector were adapted, being nebulizer attached to the mouthpiece and in 3rd phase nebulization were performance through the mouthpiece as routinely used in aerosoltherapy.
Study Design
- Study Type
- Interventional
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age between 18 and 65 years
- •Performed spirometry
- •According to the criteria of the Guidelines for Pulmonary Function-2002 published by the official organ of the Brazilian Society of Thoracic
Exclusion Criteria
- •Presence of pulmonary pathology;
- •Neurological diseases and body temperature greater than 37 º C during the initial evaluation and during intervention
- •Respiratory rate (RR) greater than 35ipm.
Outcomes
Primary Outcomes
Radioaerosol regional pulmonary deposition
Time Frame: One year
For analysis of lung deposition of radio-aerosol in the different lung areas were delineated regions of interest (ROIs), one for each lung, called the right posterior and left posterior. To analyze this deposition, the lung was divided into regions: upper, middle and bottom, and peripheral, central and intermediate.
Secondary Outcomes
- Spirometric values(One year)