Effect of L-Carnitin on Coronary Artery Bypass Graft Surgery

Not Applicable

• Conditions: Coronary Artery Bypass Graft Surgery.; Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris; I25.7

• Registration Number: IRCT20150725023332N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients with mild-to-moderate heart failure (EF = 55-40%) for coronary artery bypass graft surgery (elective CABG)

Exclusion Criteria

History of seizure or epilepsy
Patients with a history of cevebrovascular diseases
Chronic liver failure (enzymes higher than 2 times normal)
Chronic renal failure (STAGE 4 & 5)
Drinking alcohol and drugs
Coronary artery bypass surgery without using a bypass pump
CABG surgery
EF<40%

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum HS-CRP and IL-6 levels in three groups of patients. Timepoint: At baseline and 24 hours after surgery. Method of measurement: Blood sampling, blood serum isolation, and finally biochemical tests.

Secondary Outcome Measures

Name	Time	Method
Measurement of serum levels of CPK-MB and Troponin in patients undergoing surgery. Timepoint: It will be measured at baseline 8 and 24 hours after surgery. Method of measurement: Blood sampling, blood serum isolation, and finally biochemical tests.