Supplement intake test

Not Applicable

• Conditions: Glaucoma, Cataract, Diabetic retinopathy, central serous chorioretinopathy

• Registration Number: JPRN-jRCTs021180019
• Lead Sponsor: Himori Noriko

Brief Summary

Our study found that an 8-week oral course of antioxidant supplementation was effective. Dietary supplementation holds promise in the treatment of systemic oxidative stress-related diseases.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-25
• Study Completion: 2019-10-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 53

Inclusion Criteria

1.Patients with glaucoma, cataract, diabetic retinopathy, central serous chorioretinopathy
2.Glaucoma stage: Normal tension glaucoma(in medical treatment eye intraocular pressure less than 16mmHg)
Cataract:Nuclear cataract
Diabetic retinopathy:simple or non proliferative
Central serous chorioretinopathy:all
3.Age:more than 30 years old, less than 75 years old (at entry)
4.BAP:more than 1600umol/L, less than 2200 umol/L
5.dROMs:more than 300CARR
6.BMI:less than 26kg/m2

Exclusion Criteria

1.Other ophthalmic condition in hospital
2.High myopia
3.LASIK
4.After ophthalmic surgery within three months
5.Cancer patient
6.Autoimmune disease
7.Take a pill
8.other supplements intake
9.other clinical trial
10.allergy
11.pregnant, breast-feeding
12.Patient judged inappropriate by the attending physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antioxidative potential, BAP level

Secondary Outcome Measures

Name	Time	Method
oxidative stress, dROMs level, 8OHdG level, blood flow of ONH