Effect of Sleep Debt on Neurophysiological Responses to Heat Exposure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Number of errors at the Stroop test
研究概览
简要总结
Many people are required to work in stressful situations combining sleep debt and hot environmental conditions. If the effect of sleep debt on cognitive performance is proven, this effect could be increased, during heat exposure, through the deleterious effects of sleep debt on thermoregulatory abilities. These alterations may favour the occurrence of accidents.
The changes in cognitive performance induced by hyperthermia are also poorly characterised and often not dissociated from the effects of dehydration. Little is known about the effects of the combination of sleep debt and heat exposure on mental performance. Describing and understanding the alterations induced by this combined situation could provide a better understanding of the mechanisms explaining the deterioration of performance in hot conditions and promote the development of appropriate countermeasures.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 35 years old
- •Body Mass Index between 18 and 27 kg/m2
- •Body weight ≥ 54 kg
排除标准
- •Presence or history of medical pathology (cardiological, renal, hepatic, cutaneous, intestinal, neurological...)
- •Presence of a significant deviation from the normal values observed on the electrocardiogram
- •History of heat stroke
- •Known intolerance to heat (e.g. migraine sufferers)
- •Presence of a contraindication to blood sampling, notably low venous capital, belonephobia
- •Inability to ingest a capsule or refusal of the rectal probe
- •Habitual consumption of caffeine > 500 mg per day
- •Alcohol consumption greater than the equivalent of 3 glasses of wine per week
- •Consumption of narcotics
- •Smoking > 0.5 packet of cigarettes per day
- •Undergoing habitual medication
- •Pregnant or breastfeeding woman
结局指标
主要结局
Number of errors at the Stroop test
时间窗: Through study completion (25 months)
Written color names that differ from the color ink they are printed on will be displayed on a computer screen. In the first trial, the participant must say the written word. In the second trial, the participant must name the ink color instead. The higher the number of correct answers, the higher the score.
次要结局
未报告次要终点