The Impact of Misclassification of Obesity by Body Mass Index on Mortality in Patients With Chronic Kidney Disease

Completed

• Conditions: Obesity; Chronic Kidney Diseases

• Registration Number: NCT03285074
• Lead Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Brief Summary

Unlike the general population, a higher body mass index (BMI) is associated with greater survival among patients with chronic kidney disease (CKD). However, obesity is defined as excess body fat that associated with clearly elevated health risks according to the World Health Organization. In addition, muscle wasting is prevalent among CKD subjects. Thus, we hypothesized that different definition of obesity, based on BMI or body fat percentage, might have different impact on clinical outcomes among CKD population.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11-01
• Primary Completion: 2012-12-01
• Study Completion: 2017-03-31
• Status Verified: 2017-09
• Study First Submitted: 2017-09-14
• Study First Submitted QC: 2017-09-14
• Last Update Submitted: 2017-09-14
• Study First Posted: 2017-09-15
• Last Update Posted: 2017-09-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 326

Inclusion Criteria

• Subjects with non-dialysis CKD defined as estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2

Exclusion Criteria

• subjects with liver cirrhosis
• subjects with malignancy
• subjects with an acute cardiovascular event within the 3 months before screening for inclusion
• amputee
• pregnancy
• subjects with pacemaker
• subjects with metallic implant

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
all-cause mortality	medium follow up 4.9 years	all-cause mortality