Cognitive Behavioural Therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial

Completed

• Conditions: Depression; Mental and Behavioural Disorders

• Registration Number: ISRCTN38231611
• Lead Sponsor: niversity of Bristol (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08-15
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 480

Inclusion Criteria

1. Aged 18-75 years
2. Patients currently taking antidepressant medication and who have done so for at least 6 weeks at an adequate dose
3. Patients who score 14 or more on the Beck Depression Inventory (BDI)
4. Have adhered to their medication
5. Meet the World Health Organization International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) criteria for depression

Exclusion Criteria

1. Bipolar disorder
2. Psychosis or alcohol/substance abuse/dependence
3. Not able to complete the study questionnaires
4. Currently receiving CBT or other psychotherapy or secondary care for depression
5. Have received CBT in the past 3 years
6. Patients who would not be able to benefit from talking therapy without an interpreter
7. Women who are pregnant at time of recruitment will be excluded from the trial but women who become pregnant during the trial may continue, providing they have approval and permission to do so from their GP

Study & Design

• Study Type: Interventional
• Study Design: Not specified