To study inflammatory response in low pressure laparoscopic cholecystectomy compared with standard pressure laparoscopic cholecystectomy
Not Applicable
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2023/10/058338
- Lead Sponsor
- Yashwant Singh Rathore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All patients undergoing laparoscopic cholecystectomy.
2.BMI=30
3.ASA grade 1 and 2
4.18 to 65 years of age both male and female.
5.Patient is able to follow instructions.
6.Able to provide informed written consent
Exclusion Criteria
1.Age >65 or <18 years
2.BMI > 30
3.Any prior inflammatory conditions like Arthritides,chronic skin disease,IBD
4.Unable to give consent or patient refusal
5.Unfit for general anesthesia
6.Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammtory markers ( SERUM CRP,ESR, WBC COUNT,PLATELETCOUNT,serum CORTISOL,serum ALBUMIN, IL-1,IL-6,IL-17,TNF) levels at base line and 24 hours postoperatively and difference between them and compare between both groups (intervention and comparator)Timepoint: At base line and 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method Difference in surgery time among 2 groups <br/ ><br>pain scores using numerical rating scale <br/ ><br>Difference assesed by calculating average between groupsTimepoint: 24 hours postoperatively