Long-term Effects of Methadone for Cancer Pain
- Conditions
- Cancer Pain
- Registration Number
- NCT02856399
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect in neuropathic cancer pain. During a previous study the investigators find that the pain was still improving after the week 2, but they had only a small number of patients still included at this stage and they cannot conclude.
The investigators decide to follow up systematically all the patients undergoing a methadone treatment for cancer pain, at day 28, to study the hypothesis about the long-term pain improvement.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- Patients with t methadone for cancer pain in opioid rotation
- Able to fill the questionnaire
- Performance status (PS) from 0 to 2
- Patients PS 3
- Unable to sign the informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference between EVA pain score at Day 28 and Day 0 pain score measure at Day 0 and Day 28 long-term effects of methadone for cancer pain
- Secondary Outcome Measures
Name Time Method Change in quality of life score QOL C30 Day 0 and Day 28 Side effect record up to Day 28 Change in depression and anxiety score HADS Day 0 and Day 28 Change in score of neuropathic pain intensity NPSI Day 0 and Day 28
Trial Locations
- Locations (1)
Unité de Soins Palliatifs - Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet
🇫🇷Pierre-Bénite, France