Effect of use of Nasea (ramosetron) and dexamethasone on postoperative recovery in surgery without patient controlled analgesia (PCA) after surgery; Randomized Controlled Trials
Not Applicable
Recruiting
- Conditions
- Neoplasms
- Registration Number
- KCT0007007
- Lead Sponsor
- Korea University Ansan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
? Patients 19 years of age or older
? Patients managed without Patient Controlled Analgesia (PCA) after surgery
? Type of surgery: general surgery, gynecological surgery, neuro-orthopedic surgery, plastic surgery, otolaryngology surgery
? Patient who signs informed consent (ICF)
Exclusion Criteria
? Under 19 years
? Pregnant or lactating women
? Patients with hypersensitivity to the test drug (dexamethason)
? Patients who have received antiemetics, steroids, antihistamines, etc. or psychotropic drugs that may affect postoperative nausea and vomiting within 24 hours before surgery
? Patients with suspected hepato-renal disorders
? Contraindicated administration of dexamethasone, ramosetron, metoclopramide
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method verbal numerical rating scale (VNRS) was used to evaluate the patient's nausea and vomiting at 6, 12, and 24 hours after surgery.
- Secondary Outcome Measures
Name Time Method PONV incidence by surgery;PONV incidence by risk factor score (age, underlying disease, gender, previous history of nausea and vomiting, medications taken, etc.);Pain control (VAS) between ramosetron versus ramosetron + dexamethasone: reduced VAS compared to baseline;Use of the frequency of rescue drug with ramosetron and ramosetron + dexamethasone;Side effects after drug injection