Efficacy and safety of palonosetron and dexamethasone in patients who haven't responded to conventional antiemetic agents; granisetron and dexamethasone
Not Applicable
- Conditions
- Colorectal cancer
- Registration Number
- JPRN-UMIN000009584
- Lead Sponsor
- Gifu University graduate school of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1. Severe complication(s), e.g., congestive cardiac failure, coronary failure, cardiac infarction, angina pectoris, arrhythmia, cerebrovascular accident, active gastrointestinal tract ulcer, diabetes, renal failure, hepatic failure, active hepatitis or hepatic cirrhosis. 2. Symptomatic brain metastasis 3.Epilepsy patient treated with antiepileptic agent, exclusing being stable clinically 4.Combination radiotherapy 5. History of serious drug hypersensitivity for 5-HT3RA or dexamethasone. 6. History of administration of palonosetoron 7. Pregnant, nursing mothers or man who don't agree with contraception 8.Unsuitable patients judged by investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete Response rate
- Secondary Outcome Measures
Name Time Method