Comparison Of Two Drugs For Prevention Of Post Operative Nausea Vomiting During Middle Ear Surgery
- Conditions
- Health Condition 1: H66- Suppurative and unspecified otitismedia
- Registration Number
- CTRI/2019/09/021157
- Lead Sponsor
- Department Of Anesthesiology And Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients Belonging To American Society Of Anaesthesiology(ASA) Grade 1 And 2 , And Of Age Group 18 TO 60 Years With Body Weight 40 TO 80 Kg Of Either Sex Undergoing Middle Ear Surgery And Willing To Give A Written And Informed Consent.
1 Pregnant and lactating females or patients having huge abdominal mass or tumour.
2 A cancer patient who has had chemotherapy within 4 weeks prior to study entry (Screening visit) or any kind of emetogenic radiotherapy within 8 weeks prior to study entry (Screening visit).
3 Patients who had received any investigational drugs within 30 days before study entry or taken any drug with potential antiemetic efficacy within 24 hours prior to anaesthetic procedures.
4 Patients who have history of any vomiting, retching, or nausea in the 24 hours preceding the administration of anaesthesia.
5 Patients who have current history of alcohol abuse or drug abuse or taking any hormonal supplements.
6 Patients having hypersensitivity/contraindication to 5-HT3 antagonists or study drug.
7 Patients having cardio respiratory dysfunction or renal, hepatic or metabolic derangements or history of epilepsy.
8 Patients with Ryleâ??s tubes in situ.
9 Patients in varying degrees of shock during pre and post operative period.
10 Patients who will require any opioid analgesic for post operative pain relief during the period of study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post Op Nausea VomitingTimepoint: Immediately After Shifting In PAC , Than After 1 Hrs , 4 Hrs , 12 Hrs , 24 Hrs Post Op
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI