Radiographic Prediction of the Nerve Origin of Neck Peripheral Nerve Sheath Tumors

Recruiting

• Conditions: Schwannoma of Neck; Peripheral Nerve Sheath Tumors
• Interventions: Procedure: Excision

• Registration Number: NCT05684835
• Lead Sponsor: National Cheng-Kung University Hospital

Brief Summary

Postoperative nerve palsy is a major complication following resection of neck peripheral nerve sheath tumors. This study is a retrospective cohort aimed to predict the nerve origin of neck peripheral nerve sheath tumors. Accurate preoperative identification of the nerve origin can improve surgical outcomes and patient counseling

Detailed Description

Postoperative nerve palsy is a major complication following resection of neck peripheral nerve sheath tumors (PNSTs). Accurate preoperative identification of the nerve origin (NO) can improve surgical outcomes and patient counseling. This study aims to predict the NO of neck PNSTs with radiographic analysis. This study is a retrospective cohort analysis. Radiographic parameters will be reviewed and the sensitivity, specificity, accuracy of NO prediction will be evaluated.

Study Timeline

• Study Start: 2008-01-01
• Status Verified: 2023-01
• Study First Submitted: 2023-01-05
• Study First Submitted QC: 2023-01-05
• Last Update Submitted: 2023-01-12
• Study First Posted: 2023-01-13
• Last Update Posted: 2023-01-17
• Primary Completion: 2023-06-01
• Study Completion: 2023-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients with clinical diagnosis of neck peripheral nerve sheath tumors.
• Patients received surgery January 2008 and December 2022.
• The nerve origin of peripheral nerve sheath tumor must be intraoperatively confirmed.

Exclusion Criteria

• Previous anterior neck surgery.
• Malignant disease.
• Prior neck radiation.
• Undetermined intraoperative nerve origin.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Sympathetic nerve tumor group	Excision	patients with neck peripheral nerve sheath tumors originating from the sympathetic nerve
Cervical spinal nerve tumor group	Excision	patients with neck peripheral nerve sheath tumors originating from the cervical spinal nerve
Vagus nerve tumor group	Excision	patients with neck peripheral nerve sheath tumors originating from the vagus nerve

Primary Outcome Measures

Name	Time	Method
Nerve origin	within 1 month	intraoperative identification of the nerve origin of the tumor

Trial Locations

Locations (1)

National Cheng-Kung University Hospital; 🇨🇳 Taipei, Taiwan