Prevention of lower urinary tract symptoms in elderly males: the effects of an increased urine output on symptoms and bladder functioning

niversity Maastricht (UM) (The Netherlands)0 个研究点目标入组 141 人开始时间: 2007年2月20日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Males, aged between 55 and 75 years of age
•2. Gave informed consent
•3. Screened for moderate Lower Urinary Tract Symptoms (LUTS) (International Prostate Symptom Score [IPSS] : eight to 19)

•The main exclusion criteria were:
•1. The presence of mild (IPSS-score: zero to seven) or severe (IPSS-score: 20 to 35) LUTS
•2. A self reported fluid intake above 2 litres per day
•Other exclusion criteria were:
•1. The presence of diabetes
•2. Parkinson's disease
•3. Renal diseases
•4. Past surgery of the lower urinary tract
•5. A history of prostatic or bladder carcinoma
•1. The use of diuretics, medication for LUTS, or tricyclic antidepressive agents
•We excluded 1673 men on the basis of these criteria. The remaining 238 men were invited for an intake visit and for a baseline assessment. At this point participants were excluded if no baseline assessment was possible (e.g., inability to urinate in the presence of the assessor), if prostate cancer was diagnosed (Prostate Specific Antigen [PSA] more than 4.0 ìg/l followed by biopsy that confirmed the presence of a carcinoma), or if they had a serum sodium level below 130 mmol/l.

发起方

niversity Maastricht (UM) (The Netherlands)