NCT01837758已完成不适用
Changes in Platelet Function During Continuous Veno-venous Hemodialysis Using the Multiplate Device
Goethe University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2012年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- ASPItest
研究概览
简要总结
Aim of the study is a description of changes in platelet function during continuous veno-venous hemodialysis or hemofiltration in patients on an intensive care unit using the Multiplate system.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Need for a continuous renal replacement therapy
- •Platelet Count >100.000/nl
排除标准
- •Pregnancy
- •Age <18 years
- •Renal replacement therapy within the 7 days prior to enrollment
结局指标
主要结局
ASPItest
时间窗: Baseline, 6, 12, 24 and 48 hours
Area under the aggregation curve (AUC) after platelet stimulation with arachidonic acid at baseline and 6, 12, 24 and 48 hours after the start of the continuous hemofiltration.
次要结局
- ADPtest(Baseline, 6, 12, 24 and 48 hours)
- CT-INTEM(Baseline, 6, 12, 24 and 48 hours)
- MCF-INTEM(Baseline, 6, 12, 24 and 48hours)
- TRAPtest(Baseline, 6, 12, 24, 48 hours)
研究者
Saskia Wand
Dr. med Saskia Wand
Goethe University
研究点 (1)
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