Influence of Continuous Veno-venous Hemodialysis on Cerebrovascular Autoregulation in Patients With Acute Renal Failure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Renal Failure
- Sponsor
- Johannes Gutenberg University Mainz
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Change from Baseline cerebrovascular autoregulation to cerebrovascular autoregulation during continuous veno-venous hemodialysis
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
The aim of the study is to characterize the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
Detailed Description
Patients at the intensive care unit who suffered acute renal failure with the need of continuous veno-venous hemodialysis will be investigated with continuous veno-venous hemodialysis and in a time window without continuous veno-venous hemodialysis to investigate the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
Investigators
Patrick Schramm
Senior Physician
Johannes Gutenberg University Mainz
Eligibility Criteria
Inclusion Criteria
- •acute renal failure
- •need for continuous veno-venous hemodialysis
- •age \>18 Years
Exclusion Criteria
- •Preexisting cerebral illness
- •traumatic brain injury
- •Meningitis or encephalitis
- •Pregnancy
Outcomes
Primary Outcomes
Change from Baseline cerebrovascular autoregulation to cerebrovascular autoregulation during continuous veno-venous hemodialysis
Time Frame: 1 Year
Is there an influence of continuous veno-venous hemodialysis at the cerebrovascular autoregulation, which would be a side effect with limiting use in patients with brain injury or the need of intensive monitoring of cerebral perfusion pressure in this patients.