Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method

Completed

• Conditions: Renal Dialysis
• Interventions: Device: bioreactans tool

• Registration Number: NCT03905122
• Lead Sponsor: Trakya University

Brief Summary

Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Detailed Description

Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. Dialysis in the hemodialysis unit is a method used in intensive care patients and is preferred especially in patients with stable hemodynamics. In dialysis methods, changes occur frequently in the body fluids of the patient. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. As a result of measurements with buioreactans method, fluid balance in patients will be understood more easily. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Study Timeline

• Study Start: 2018-06-15
• Study First Submitted: 2018-12-24
• Study First Submitted QC: 2019-04-03
• Study First Posted: 2019-04-05
• Primary Completion: 2020-06-15
• Study Completion: 2020-06-15
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-06
• Last Update Posted: 2020-10-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• patients required dialysis therapy

Exclusion Criteria

• under 18 years old
• confirmed or undiagnosed brain death

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
continous veno-venous hemodialysis	bioreactans tool	to measure the fluid changes by using bioreactance method in continous veno-venous hemodialysis group
hemodialysis	bioreactans tool	to measure the fluid changes by using bioreactance method in hemodialysis group

Primary Outcome Measures

Name	Time	Method
change in Cardiac Output	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours	change in Cardiac Output
change in Cardiac Index	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours	change in Cardiac Index
change in thoracic fluid content	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours	change in thoracic fluid content
change in stroke volum	before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours	change in stroke volum

Trial Locations

Locations (1)

Trakya University; 🇹🇷 Edirne, Turkey