Reducing Hemodialysis Catheter Use in in a Prevalent Hemodialysis Population; A Pilot Randomized Control Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Hemodialysis
- Sponsor
- Dr. Lisa Miller
- Enrollment
- 3
- Locations
- 1
- Primary Endpoint
- The proportion of patients using a CVC in a prevalent hemodialysis population after the implementation of an algorithm protocol to convert the CVC to an AVF compared with patients who received current standard care.
- Status
- Terminated
- Last Updated
- 12 years ago
Overview
Brief Summary
To determine if a protocolized approach to converting hemodialysis central venous catheters (CVC) to arteriovenous fistulae will improve rates of functioning AVF and decrease CVC use.
Detailed Description
In order to receive dialysis, patients require repeated access to their bloodstream. This access can be either via a central venous catheter (CVC) or a surgically created arteriovenous fistula (AVF) or graft (AVG). This is a pilot randomized control trial of prevalent hemodialysis patients with a central venous catheter (CVC), to determine if a systematic approach using an algorithm protocol to convert the CVC to an AVF (arteriovenous fistula) will improve rates of functioning AVF and decrease CVC use. The algorithm (intervention group) will be compared to current practice (control group), a non-standardized approach at the discretion of the caring nephrologist and/or surgeon.
Investigators
Dr. Lisa Miller
Dr. Lisa Miller
University of Manitoba
Eligibility Criteria
Inclusion Criteria
- •\> 18 years of age
- •Dialyzing with a CVC
- •Receiving hemodialysis three times weekly for \> 3 months
Exclusion Criteria
- •Awaiting peritoneal dialysis catheter insertion
- •Scheduled living donor transplant
- •Transient patients from out of province
- •Expected transfer to satellite dialysis unit within 6 months
- •Surgical plan for AVF (i.e. scheduled date)
- •Documented lack of suitable vasculature for AVF
- •Refusing AVF
Outcomes
Primary Outcomes
The proportion of patients using a CVC in a prevalent hemodialysis population after the implementation of an algorithm protocol to convert the CVC to an AVF compared with patients who received current standard care.
Time Frame: 9 months
Secondary Outcomes
- Proportion of patients with a maturing AVF(9 months)
- The proportion of patients with a functioning AVF after the implementation of an algorithm protocol to convert the CVC to an AVF compared with patients who received current standard care.(9 months)
- Primary fistula failure rate(9 months)
- Incidence of AVF salvage procedures, including balloon angioplasty and accessory vein ligation, within 9 months of AVF creation(9 months)