NL-OMON55192
Recruiting
Not Applicable
Exploring bleeding risk and platelet function combined with multiple omics techniques in 22q11.2 deletion syndrome - Platelet function in 22q11.2DS
Medisch Universitair Ziekenhuis Maastricht0 sites60 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- DiGeorge syndrome
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- 16 years or older.
- •\- signed informed consent.
- •Adults with 22q11\.2DS
- •\- molecularly confirmed 22q11\.2 deletion syndrome.
- •\- Mentally competent (ability to give informed consent) and aged 16 years and
- •older or, in case
- •the individual is mentally incompetent aged 16 years and older, consent will be
- •given by the legally authorized representative of the subject.
Exclusion Criteria
- •\- The presence of any malignancy.
- •\- Use of antiplatelet or anticoagulant drugs within the last two weeks prior to
- •\- Use of anti\-inflammatory drugs within the last two weeks prior to the study.
- •\- auto\-immune thrombocytopenia
- •Specific for healthy controls:
- •\- A medical history of thrombocytopenia (\<150\.000 platelets per mL).
- •\- Increased bleeding risk, defined as a diagnosed bleeding disorder.
- •\- Metabolic disorder.
Outcomes
Primary Outcomes
Not specified
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