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Thrombogenicity and platelet reactivity as risk factors for postoperative microemboli signals in patients undergoing carotid endarterectomy

Conditions
strokecarotic endarterectomy blood coagulation platelet reactivityberoerte carotis endarteriectomiebloedstollingplaatjesfunctie
Registration Number
NL-OMON25062
Lead Sponsor
MUMC
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

1. Patients with an ischemic stroke or TIA (first episode or recurrent disease) AND:
an ipislateral stenosis of the carotid artery for which operation of the carotid artery is indicated.

Exclusion Criteria

1. Proven coagulopathies

2. Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Amount of MES signals (mean and SD) during TCD monitoring start from the first postoperative hour during a period of 3 hours in relation to thrombogenicity and platelet reactivity
Secondary Outcome Measures
NameTimeMethod
- Postoperative stroke in realtion to thrombogeniticity and platlet reactivity during 1 year follow-up<br /><br>- Postoperative stroke (asymptomatic) during 7 days follow-up starting from operation day, detected by MRI
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