Comparison of Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid: a Prospective Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hysterectomy
- Sponsor
- Mayo Clinic
- Enrollment
- 152
- Locations
- 1
- Primary Endpoint
- rates of urinary tract infections at 6-9 days post-operative
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Our study will compare the rates of postoperative urinary tract infections (UTI) between patients who undergo cystoscopy using 50% dextrose injection plus bladder washout versus normal saline after hysterectomy for benign indications. Primary outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
Detailed Description
This will be a prospective cohort study of the rate of UTIs after cystoscopic distention media of normal saline with maximum injection of 40 cc of 50% dextrose plus 300 cc of normal saline washout versus normal saline after hysterectomy for benign indications. A pre-operative urine culture will be obtained via mid-stream clean catch prior to administration of routine pre-operative prophylactic antibiotics. At 6-9 days post-operatively, a repeat urine culture will be obtained via mid-stream clean catch. Appropriate treatment will be administered if the urine culture is positive.Primary outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
Investigators
Johnny Yi
Principal Investigator
Mayo Clinic
Eligibility Criteria
Inclusion Criteria
- •Preoperative scheduling CPT codes for hysterectomy
Exclusion Criteria
- •Discharged home with indwelling foley catheter
- •Indwelling foley catheter \> 24 hours
- •Ureteral injury
- •Chronic immunosuppression
- •History of diabetes
- •Recurrent UTIs (≥2 infections in six months or ≥3 infections in one year)
- •Reported Chronic Kidney Disease
- •Renal anomalies
Outcomes
Primary Outcomes
rates of urinary tract infections at 6-9 days post-operative
Time Frame: 6-9 days post-operative
be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter