Comparison of Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid: a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 152
- 试验地点
- 2
- 主要终点
- rates of urinary tract infections at 6-9 days post-operative
研究概览
简要总结
Our study will compare the rates of postoperative urinary tract infections (UTI) between patients who undergo cystoscopy using 50% dextrose injection plus bladder washout versus normal saline after hysterectomy for benign indications. Primary outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
详细描述
This will be a prospective cohort study of the rate of UTIs after cystoscopic distention media of normal saline with maximum injection of 40 cc of 50% dextrose plus 300 cc of normal saline washout versus normal saline after hysterectomy for benign indications.
A pre-operative urine culture will be obtained via mid-stream clean catch prior to administration of routine pre-operative prophylactic antibiotics.
At 6-9 days post-operatively, a repeat urine culture will be obtained via mid-stream clean catch. Appropriate treatment will be administered if the urine culture is positive.Primary outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
盲法说明
Participant masked to distention media
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Preoperative scheduling CPT codes for hysterectomy
排除标准
- •Discharged home with indwelling foley catheter
- •Indwelling foley catheter > 24 hours
- •Ureteral injury
- •Chronic immunosuppression
- •History of diabetes
- •Recurrent UTIs (≥2 infections in six months or ≥3 infections in one year)
- •Reported Chronic Kidney Disease
- •Renal anomalies
结局指标
主要结局
rates of urinary tract infections at 6-9 days post-operative
时间窗: 6-9 days post-operative
be rates of urinary tract infections at 6-9 days post-operatively. This will be defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units per milliliter
次要结局
未报告次要终点