Effects of a Cognitive Interference Task on Alcohol Craving and Consumption Among Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Average Drinks Per Occasion
研究概览
简要总结
The purpose of this study is to test a brief task of playing the game Tetris to reduce alcohol cravings and alcohol use. Women who are seen at primary care and recruited through the community will be asked to rate alcohol craving and use for a 1-week baseline period. Then they will be randomly assigned to play the Tetris game on their phones daily or to a control condition for a 2-week period. Participants will also complete a cue-reactivity task, that involves viewing pictures of alcohol and rating cravings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female, any race or ethnicity, age 21 to 65 years old.
- •Able to comprehend English.
- •At least one heavy drinking per week (i.e., consuming at least four or more drinks in one day) for the last two weeks
- •Internet access and reliable electronic device
排除标准
- •More than four heavy drinking days per week.
- •Currently engaged in treatment for Alcohol Use Disorder (AUD).
- •Current clinically significant bipolar affective disorder, schizophrenia, or psychotic disorder.
- •Imminently suicidal or homicidal.
- •Participants taking psychoactive medications that may affect alcohol craving or consumption.
- •A score of 10 or higher on the Clinical Institute of Alcohol Withdrawal Revised (CIWA-R).24
结局指标
主要结局
Average Drinks Per Occasion
时间窗: Participants reported alcohol consumption one month after the intervention.
Participants completed the Timeline Follow Back, which assesses past-month alcohol consumption. The outcome measure is average drinks per drinking occasion. Scores ranged from 0 to 6.29 drinks. Higher scores indicate greater average drinks consumed per occasion.
Number of Standard Drinks
时间窗: Participants reported number of standard drinks each morning at a scheduled time for 14 days.
Participants reported the number of standard drinks consumed yesterday. The scale ranged from 0 to more than 20. Higher scores indicate more drinks consumed. A single value for number of standard drinks reported each day for 14 days was averaged across all participants.
Changes in Alcohol Craving Before and After Tetris Task
时间窗: Participants reported pre- and post-task alcohol craving up to three times per day for a 14-day intervention period. Post-task craving was measured right after the Tetris task/control break and pre-task craving was measured directly before.
During the intervention phase, participants received up to three daily random in-vivo assessments assessing craving. Participants in the experimental group completed a Tetris task if they reported a positive response to craving and participants in the control group took an equivalently long break. Participants then re-rated their craving. Both craving assessments used a single item from the Visual Analogue Craving Scale ("How strong is your craving for alcohol RIGHT NOW?"), ranging from 0 to 100. The outcome measure represents change in craving, calculated as post-task craving minus pre-task craving. The change score was the difference in craving before and after the experimental task or the wait period. A single value for change in alcohol craving reported at each assessment during the 14 days was averaged across all participants.
Changes in Alcohol Craving Before and After Cue Tetris Task
时间窗: Participants reported pre- and post-task alcohol craving up to once a day for a 14-day intervention period. Post-task craving was measured right after the CREMA/wait period and pre-task craving was measured directly before.
During the intervention phase, participants received a daily Cue Reactivity Ecological Momentary Assessment (CREMA), which provides real-time responses to alcohol-related imagery. After the CREMA, participants in the experimental group completed a Tetris task and participants in the control group took an equivalently long break. Participants then re-rated their craving. Both craving assessments used a single item from the Visual Analogue Craving Scale ("How strong is your craving for alcohol RIGHT NOW?"), ranging from 0 to 100. The outcome measure represents change in craving, calculated as post-task craving minus pre-task craving. A single value for change in alcohol craving reported at each cue reactivity assessment during the 14 days was averaged across all participants.
Alcohol Craving
时间窗: Participants reported cravings one-month after the intervention.
Participants completed the 4-item imagery subscale of the Craving Experiences Questionnaire, which measures craving/intense desire. Items are rated on a 0 to 10 point scale. A mean was calculated from the 4-item imagery subscale, with a possible range of 0 to 10. Higher scores indicate greater alcohol craving.
次要结局
- Drinking Motives(Participants reported drinking motives at baseline.)
- Obsessive Thoughts About Alcohol(Participants reported obsessive thoughts about alcohol at a single baseline assessment, which occurred the day before the EMA period began.)
- Acceptability Ratings(Recorded within one-week after the intervention.)
- Feasibility of Intervention(This was recorded during the 14-day intervention phase.)
研究者
Christine Hahn
Research Assistant Professor
Medical University of South Carolina