Effects of esomeprazole on symptoms indicative of gastroesophageal reflux disease observed in patients taking non-steroidal anti-inflammatory drugs (NSAIDs)
Not Applicable
Completed
- Conditions
- Patients who scored more than 8 on F scale questionnaire after taking NSAIDs more than 4 weeks are enrolled.
- Registration Number
- JPRN-jRCT1091220218
- Lead Sponsor
- Department of Orthopedic surgery, graduate school of medicine, Chiba University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Patients who scored more than 8 on F scale questionnaire after taking NSAIDs more than 4 weeks are enrolled.
Exclusion Criteria
1 Those who have bleedings from gastrointestinal system, sudden decrease of body weight
2 Those who have organic brain damage, schizophrenia
3 Alcohol dependency, drug abuse
4 Hormonal disorders such as hyperthyroidism
5 Severe renal or liver dysfunction, hematopoietic disorders
6 Those who take more than two anti-coagulants
7 Those who are allergic to drugs to be tested
8 Those who are pregnant or who wish to be pregnant during corresponding clinical test
9 Patients who are not regarded as improper by physician in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FSSG scale
- Secondary Outcome Measures
Name Time Method Subscores of FSSG scale