Skin Imaging With Technologies in Development

Recruiting

• Conditions: Pigmented Skin Lesion of Uncertain Nature
• Interventions: Device: non-invasive imaging modalities for assessment of skin

• Registration Number: NCT00764920
• Lead Sponsor: University of California, Irvine

Brief Summary

The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Detailed Description

Normal and lesional skin will be assessed by the following imaging modalities:

1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.

2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.

3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.

4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.

5. Multiphoton Microscopy can provide images of structures of the skin.

Study Timeline

• Study First Submitted: 2008-09-30
• Study Start: 2008-10
• Study First Submitted QC: 2008-10-01
• Study First Posted: 2008-10-02
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-12
• Last Update Posted: 2024-08-14
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 750

Inclusion Criteria

• adult male or female 7 and older; able to carry out study instructions

Exclusion Criteria

• Younger than 7 years old
• pregnant woman
• breast feeding

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Skin Imaging	non-invasive imaging modalities for assessment of skin	non-invasive imaging modalities for assessment of skin

Primary Outcome Measures

Name	Time	Method
Collect information on normal and lesional skin	up to 12 weeks	Develop non-invasive imaging modalities for assessment of skin.

Trial Locations

Locations (1)

Beckman Laser Institute Medical clinic; 🇺🇸 Irvine, California, United States