Effect of selenium supplementation on glutathione peroxidase enzyme activity in patients with chronic kidney disease
Phase 2
- Conditions
- Chronic kidney disease.Chronic kidney disease
- Registration Number
- IRCT201305318501N2
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1) Patient with chronic kidney disease for = 3 month
2) patients= 20 years and<65 years3) Plasma albumin level 4 g/dl
Exclusion criteria:1) Acute infection 2) Recent acute myocardial infarction during 6 week ago 3) Recent consumption of antioxidant drugs (for example vitamine A, E, C) 4) Active smoking 5) History of new or old cancer 6)Liver failure
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glutathione peroxidase enzyme activity. Timepoint: Before study, Three months after drug supplementation. Method of measurement: ELISA (Kit made by UK).
- Secondary Outcome Measures
Name Time Method Selenium plasma level. Timepoint: Before study, Three months after drug supplementation. Method of measurement: Electrothermal atomic absorbtion spectrometry(ETAAS).