Comparision of etidronic acid and propolis as irrigants against primary teeth root canal microorganism

Phase 1

Not yet recruiting

Conditions: Pain, unspecified,

Registration Number: CTRI/2020/08/027096

Brief Summary: An interventional, double blinded, randomised parallel group trial willbe conducted in 30 teeth from the patients requiring pulpectomy of 3 to 8 yearsold after obtaining a written informed consent from the parents of child. 30 teeth requiring pulpectomy will be divided into two groups using followingirrigants: Group I (n=15 teeth): 9% Etidronic acid and Group II (n=15 teeth):Propolis. Appropriate local anesthesia will be given and the tooth will beisolated with rubber dam. The gross carious tissue will be removed and initialaccess opening will be done with No. 3 round carbide bur. Working length willbe determined with preoperative intraoral periapical radiograph. Firstmicrobiological sample will be obtained with 2 sterile absorbent paper pointseach for 30 seconds from the root canal (pre irrigation) and will beimmediately immersed into test tube with Brain Heart Infusion Broth (BHI).Conventional biomechanical preparation will be done upto 35 k-file. Duringinstrumentation after each file, Group I: 2 ml of 9% Etidronic acid for 20seconds will be used as an irrigant and Group II: 2 ml of Propolis for 20 seconds will be used as anirrigant. The activation of irrigants will be done with waterpik. Finalirrigation of canals will be done at the end of instrumentation and driedbefore obturating and second microbiological sample will be collected withanother 2 sterile absorbent paper points each for 30 seconds. The root canalwill be filled with a obturating material and a postoperative intraoral periapicalradiograph will be taken. The collected samples will be subjected tomicrobiological analysis to determine the number of colony forming unitsagainst E. faecalis. The obtained results will be subjected to statisticalanalysis.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patients having optimum systemic health.
Primary teeth with atleast one necrotic pulp canal, abscess, or sinus tract.
Primary teeth with presence of radiolucency in furcation or periapical region.
Primary teeth with atleast two thirds of root present.
Sufficient tooth structure to support a rubber dam.

Exclusion Criteria

Patient on antibiotics upto 2 weeks prior to the study or having any systemic illness.
Primary teeth which are non restorable,with pulpal floor or with mobility.
Primary teeth with less than two thirds present.
Teeth which doesnot support rubber dam application.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Etidronic acid may have better antimicrobial property than Propolis as an irrigant in primary teeth	1 year

Secondary Outcome Measures

Name	Time	Method
Etidronic acid may be equally efficient to Propolis in antimicrobial activity as an irrigant in primary teeth	1 year

Trial Locations

Locations (1): GSL Dental College and Hospital
🇮🇳
Godavari, ANDHRA PRADESH, India
GSL Dental College and Hospital
🇮🇳Godavari, ANDHRA PRADESH, India
Atluri Naga Supraja
Principal investigator
9866834589
supraja.atluri@gmail.com