The accuracy of carotid, femoral and brachial artery measurements compared to conventional intra-vascular methods of flow-related parameters

Completed

• Conditions: 10019280; blood flow measurements; non-invasive cardiac output monitoring

• Registration Number: NL-OMON46523
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Adult patient (age > 18 years)
- Elective open GI surgery
- ASA 1-2
- Invasive arterial blood pressure monitoring
- Informed consent

Exclusion Criteria

- Known significant occlusion, recent intra-arterial intervention or abnormal anatomy of aortic, femoral, carotid or brachial artery
- Cerebrovascular accident
- Atrial fibrillation or supraventricular tachycardias
- COPD stage 3-4
- Lobectomy / pneumectomy
- Active pneumonia
- Cardiac failure
- Severe heart valve regurgitation or stenosis (grade 3+)
- Not able to measure brachial or carotid artery blood flow during surgery
- Contra-indications for femoral arterial catheter placement (e.g., vascular graft)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Femoral, carotid and brachial ultrasound determined blood flow, intermittent<br /><br>transpulmonary thermodilution cardiac output and stroke volume determined by<br /><br>pulse-contour analysis (invasive and non-invasive) right before induction and<br /><br>under anaesthesia. When a change in preload is anticipated (e.g. a fluid bolus,<br /><br>start of vasopressors, and Trendelenburg position), before and after this<br /><br>preload change measurements will be performed.</p><br>